I was using Sublime Text2 and all of a sudden it wouldn't save a file. I kept getting a permissioning error: "Can't save file 'x'. It took a little while, and a little aggravation, to figure out what happened. Windows 8 just went through another of it's forced upgrades and the admin rights for Sublime Text to write to the C:\inetpub folder was revoked.
The solution is to right click on the application and give yourself admin rights.
Back to work.